Glucagon-like peptide1(GLP-1) is a gastrointestinal hormone with pleiotropic functions, including vasodilatory and vasculoprotective effects. AsGLP-1increases after a meal, it could be involved inadiposetissueblood flow (ATBF) regulation.
Results suggest thatfastinginducesadipose-specific insulin resistance in elephant seal pups, while maintaining skeletal muscle insulin sensitivity, and therefore suggests that the onset of insulin resistance infastingmammals is an evolved response to cope withprolongedfood deprivation.
The results presented in this review highlight the potential of nutritional and physiologic stimulation ofGLP-1secretion. Further research onfastingandpostprandialGLP-1concentrations and the resulting metabolic consequences under different metabolic conditions is needed.
Adiposetissue(AT) inflammation is strongly associated with obesity and constitutes an obesogenic memory upon weight loss. Here, the authors show that intermittentfastingleads to an adipocyte ...
Such details provide a deeper understanding and appreciation for Prolonged Fasting And Glp 1 Receptor Expression In Adipose Tissue Depots.
Harney et al. show that every-other-dayfastingimproves metabolic health in mice in the absence of weight loss and examine the proteomic response of several keyadiposedepots. They finddepot-specific increases in mitochondria, suppression of lipolysis, increased fatty acid synthesis, and changes in extracellular matrix content.
Abstract There is widespread interest infastingas a therapeutic or preventive regi-men for improving health. This review provides an overview of the impact offastingonadiposetissuemetabolism, with special attention to sexually dimorphic regulation. Duringfasting, the storage of triacylglycerols inadi-posetissueis inhibited via suppression of the extracellular lipolytic enzyme ...
Conclusion: The present findings showed thatfastinghas no significant effect on theGLP-1andlipid profile indices of the obese and thin women. KeywordsfastingGlucagon-like peptide-1 hormone ...
