Neonates are particularly susceptible to malnutrition due to their limited reserves of micronutrients and their rapid growth. In the present study, we examined the effect ofvitaminCdeficiency on markers ofoxidativestressin plasma, liver and brain of weanlingguineapigs.VitaminCdeficiency caused rapid and significant depletion of ascorbate (P < 0·001), tocopherols (P < 0·001) and ...
Oxidativestressand damage markers inguineapigcerebral cortex were assessed at preterm and near term gestational time points with and without maternal VitC deficiency as a potentialoxidativeinsult.

This particular example perfectly highlights why Guinea Pig Vitamin C Oxidative Stress is so captivating.
Oxidativestressand damage markers inguineapigcerebral cortex were assessed at preterm and near term gestational time points with and without maternal VitC deficiency as a potentialoxidativeinsult.

In the present study, we examined the effect ofvitaminCdeficiency on markers ofoxidativestressin plasma, liver and brain of weanlingguineapigs.VitaminCdeficiency caused rapid and significant depletion of ascorbate (P,0001), tocopherols (P,0001) and glutathione (P,0001), and a decrease in superoxide dismutase activity (P¼0005) in the ...

The present study comparedoxidativestressof ageing to that of a long-term non-scorbuticvitaminCdeficiency inguineapigs.
The results show that the selective preservation of brain ascorbate and induction of DNA repair invitaminC-deficient weanlingguineapigsis not sufficient to preventoxidativedamage.VitaminCdeficiency may therefore be particularly adverse during the neonatal period.
Etiopathology and effects of hypovitaminosiscinguineapigsVitamincdeficiency led to impaired production of collagen, laminin, elastin causing various type of physical and physiological problems ranging from lameness due to painful swollen joint to dental, skin, digestive, problems. Asvitamincis known to maintain the morphological appearance of endothelium and smooth muscles components ...