March 5, 2026 -Several other breeds are widely referenced as causing a diminished immune reaction in cat allergy sufferers, including Sphynx, Russian Blue, Cornish Rex, Devon Rex, Siamese, Javanese, Oriental Shorthair, Burmese, and LaPerm. Fairly reliable tests for their Fel d 1 protein production is available for individual cats, but research regarding entire breeds continues, hampered by the lack of a thoroughly accessible and accurate genetic test for production of the antigen.
This statement is true regardless of their breed, hair length, and the intensity of shedding. Returning to the topic of Siamese cats,they actually produce less of the Fel d 1 protein responsible for triggering allergies in people.

August 30, 2023 -I have severe cat allergies to male cats, as they carry more of the protein that causes allergies, Fel d1. Female cats carry less- I had a female cat growing up that I was fine with. My Siamese is a boy, and I’m severely allergic to him (didn’t find this out until after adopting). So I don’t think the breed makes a difference but it is proven that a female cat will cause you less problems, so that’s what I advise.

August 22, 2025 -While reducing dust, dander, and ... severefeline asthma may require an inhaler or lifelong oral medications. Amyloidosis refers to a group of diseases caused by abnormal deposition of the fibrous protein amyloid into various tissues of the body. Amyloidosis disrupts the normal functions of these areas, and can lead to conditions such as liver failure and kidney disease. Siamese cats are believed to have a genetic mutation that increases their vulnerability to amyloidosis...

This particular example perfectly highlights why Chronic Fel In Siamese Breed is so captivating.